The Fourth Treatment for Medical Refugees


by Nakamachi Nobuhiro Yoshimizu, M.D., Ph.D., Garden Clinic Director

Chapter 5
Supplement Therapy Improves the Immune System

Fight with cancer based on the immune system,
apoptosis and angiogenesis

A simple intake of supplements will not magically improve the immune system. We should approach the treatment based on three mechanisms.

Firstly, improvement of the immunity that inhibits cancer growth. Secondly, inhibition of the angiogenesis that provides a nutritional supply to the cancer cells.

Thirdly, lead the cancer cells into apoptosis.

These three treatment approaches were first introduced by Dr. Abe from the Qudan Clinic. His clinic provides customized treatments for each patient by utilizing genetic analysis and activated lymphocyte treatments.

Firstly, we can use immune reinforcement supplements that contain black yeast, the agaricus mushroom, and βglucan. In addition, substances like lactobacillus and oligosaccharide that improve the intestinal condition may be useful as well, and we can use vegetable extracts rich in vitamin and mineral contents.

These treatment modalities will reinforce the natural immune system in the body.

Secondly, we can use supplements that inhibit new blood vessel growth. If we are able to inhibit angiogenesis, the cancer cells will not be provided with enough nutrition.

Substances that are useful are fucoidan, shark cartilage, chondroitin, and turmeric. It is also important to refrain from ingesting any fat or sugar that may aid the cancer's nutrition.

Thirdly, it is important to lead the cancer cells into apoptosis because they are much more resistant to apoptosis than normal cells. Substances like black yeast, mushrooms can have those effects.

Based on these three approaches, we can treat patients with various supplements based on the patient's condition. We can also adjust the treatment modalities based on the patient's budget.

The most important part of our treatment has to do with food. When food enters the gastrointestinal system, it activates the immune system. Dr. Koshima, the founder of Interferon, said that, "when food is taken into an oral route, it stimulates the Peyer's patch in the intestine and activates the macrophages. Then, it will produce interferons that inhibit the growth of cancer cells and virus replications." Pumpkin seeds, turmeric, and adlay are known to promote the synthesis of interferons.

Basic cancer treatment strategies

basic cancer treatment strategies

Therefore, as long as the patient has a good gastrointestinal function, there is a good chance of curing even end-stage cancer.

Change the intestinal environment that is favorable
to Bifidus using fructo-oligosaccharides

The next thing that we must consider is changing the intestinal environment to become favorable to good microbes.

Today, the intestines of Japanese people are very favorable to bad microbes because of the Western eating style that prefers instant food and processed food. Since people do not consume enough vegetable fibers, bad microbes such as clostridium perfringens produce a lot of nitrosoamine and cause colon cancer.

Therefore, it is important to consume fructooligosaccharides to change the intestinal environment into a favorable environment for good microbes.

The effects of Bifidus have been reported by Tokyo University's Professor Hakarioka, who published the paper "An intestinal environment that prevents aging and colon cancer".

  1. It protects our body from bacterial infection.
    — Bifidus breaks down glucose and produces lactates to inhibit the growth of bacteria within the intestines.
  2. It synthesizes vitamins.
    — It synthesizes vitamins B1, B2, B12, K1, K2, nicotinic acid and folic acid.
  3. It promotes intestinal movements and prevents constipation.
    — Bifidus breaks down glucose and produces lactate to reinforce the Supplemental therapy improves the immune system.
  4. It prevents diarrhea and colitis.
    — It weakens bacterial activities.
  5. It improves the body's immune system.
    — Bifidus secretes substances that improve the body's immune system.
  6. It disintegrates oncogenic materials.
    — Bifidus inhibits the secretion of various oncogenic substances like nitrosoamine.
  7. It promotes the absorption of calcium and iron.
    — It promotes the absorption of organic acids.

In addition, it has been reported that Bifidus not only produces lactates but also butyric acid that inhibits the growth of cancer cells.

In other words, an intestinal environment that is favorable to good microbes results in a supply of fresh nutrition and oxygen to the entire body. Therefore, people who do not have constipation and cancer can also benefit from eating fructooligosaccharides to improve the intestinal environment. Since it can prevent colon cancer, it is strongly recommended.

Over-consumption of lineolic acid
is the cause of metabolic syndrome

Before taking the supplements, an adequate amount of fatty acid is also very important. One of the causes of metabolic syndrome is the intake of linoleic acid in animal fat, corn oil and cooking oil. Linoleic acid refers to an essential fatty acid in the Omega 6 family. It is synthesized from arachidonic acid within the body and promotes inflammation and coagulation

Substances such as DHA, EPA, linseed oil, and other fish oils are in the Omega 3 family and contain a lot of alpha-linoleic acid, which inhibits allergic reactions and inflammation.

Therefore, it is important to consume a lot of fish such as mackerel. It is also very important to change cooking oil to linseed oil. When people consume alpha-linoleic acid from the Omega 3 family, the body's cholesterol level will be improved as well as the brain functions.

According to Dr. Yamada, the economic growth of the nation has allowed people to consume more animal fat in their meats and caused more obesity and hyperlipidemia. That is when the government started to recommend the intake of linoleic acid in order to decrease the cholesterol level in the body. However, after much research, it was discovered that linoleic acid does not decrease the blood cholesterol level.

Rather, it was associated with atherosclerosis, colon cancer, breast cancer, allergic diseases, Crohn's disease, and other inflammatory diseases. As a result, Dr. Yamada and the Japanese Fatty Acid Nutrition Association published "Recommendations to decrease linoleic acid consumption" in 2002, based on data between 1980 and 1995, when the consumption of linoleic acid increased dramatically. Even though the recommended intake of linoleic acid is 7 grams per day, the consumption rate is 13 grams/day in normal Japanese people and in fact, Japanese people consume more linoleic acid than American people.

Omega 3 and Omega 6 have an antagonist effect on each other. When the balance between the two is compromised, various troubles are caused in neurons and blood vessels. The Ministry of Health, Labor and Welfare are still saying that the consumption ratio of Omegas 3 and 6 are 1:4. However, the current recommendation for the consumption ratio is 1:2 or 1:1.

The intake of fish, linseed oil, and other products rich in EPA, DHA, and alpha linoleic acid, will improve cell membranes' composition. It will promote easy energy facilitation in the mitochondria and improve the metabolism process. It also improves learning disabilities and other allergic diseases like atopic dermatitis.

Molecules high in polysaccharide stabilize
a cell's glucose chain

We have been using mushroom supplements because we believed that the β 1~3 and 1~6 glucans in the mushroom will reinforce the immune system. However, we have discovered that the polysaccharide chain on the cell surface acts as an antenna for the cells and plays a significant role in maintaining health.

We have also discovered that this is made from yeasts, mushrooms, fruits, vegetables, and other polysaccharides.

In the current research on these polysaccharides, it has been reported that, "glucose chains on the cell surface are highly associated with atopic dermatitis, renal failure, rheumatism and other diseases." In other words, the decrease of the glucose chains is the cause of many diseases.

Therefore, by supplying patients with polysaccharides that act as a building block for these glucose chains, diseases like AIDS and atopic dermatitis were significantly improved after the treatment.

The nutrition that builds this glucose chain is found in black yeast, glucosamine, chondroitin, honey cookies, fucoidan, and aloe. From these products, we chose to use an extract drink of black yeast, Agarose, meshimacope, and mushrooms. The drink was made based on the research from Tokyo University and Fukuri University.

Black yeast is made during the process of sugar manufacturing. It has been ionized and contains β1, 3~1 and 6 glucans, oligosaccharides, polysaccharides, inositol, and ferulic acid. It is a high molecule polysaccharide composed of 100,000 to 500,000 units. Mushrooms also improve the immune function as well as the kidney function. Since people are sensitive to different substances, it is important to combine these substances for the maximum treatment effect.

Glucose chains help to maintain life

Then, what are the functions of glucose chains?

They are on the cell surface and act as an antenna that detects viruses, toxins, cancer cells, and bacteria within the body. They signal to the white blood cells after detection and balance the hormonal secretion system as well. In addition, they play a significant role in the communication between cells to coordinate the transportation of various nutrients and signals.

The Integrated Research Center for Elderly Patients reported that all of the 60 trillion cells are covered with glucose chains made from proteins and fats. These glucose chains have a basic structure made from three mannose and two N-Acetyl-Glucosamines. Then, glucose branches made out of N-galactose, fructose, and sialic acid are attached to the basic structure. There were cases where some cells lacked in these glucose chains. The disease was named congenital disorder of glycosylation (CDG) and showed neurological /motor symptoms. It was also correlated with chronic rheumatism and autoimmune diseases.

The report concluded that by studying the functions of these glucose chains, they hope to find the causes of cancer and

other incurable diseases.

stabilizing glucose

High improvement rate in 100 asthma patients,
confirmed by NIH

High improvement rate in 100 asthma patients, confirmed by NIH

NIH, a world-renowned cancer institution, reported that sthma patients' conditions improved when they were administered with 8 basic monosaccharides. The 8 types of monosaccharides are glucose, galactose, mannose, fructose, xylose, N-acetyl-glucosamine, N-acetyl-galactosamine, and N-acetyl- neuraminic acid.

It has been reported that glucose and galactose can be synthesized easily within the body by consuming carbohydrates and milk. However, the human body was lacking in the other 6 monosaccharides, which may be the cause of many of the diseases that we are suffering from.

As we have discussed before, food additives, pesticides and psychological stresses are the factors that interfere with glucose chain synthesis. We believe that when these glucose chains are destroyed, diseases like immunodeficie-ncy occur.

Not only beneficial to cancer treatment, glucose chain supplements are also very effective in treating atopic dermatitis and asthma. Therefore, it is extremely important to use supplements that normalize the glucose chain.

Activate enzymes by consuming physiological minerals

There is another important strategy that must be considered when taking supplements.

Other than supplying the essential minerals, it is important to drink bottled water that contains iron, zinc, cobalt, magnesium, molybdenum, fluorine, silica, nickel and many other minerals that are needed in our body. Water that contains these variable minerals comes from Abukuma Mountain which has been dissolving mountain minerals for 80 million years.

It is extremely friendly to our body and allows us to consume the various minerals that our bodies need.

Since the vegetables and fruits grown in modern agriculture lack in minerals, our body is not supplied with a sufficient amount of minerals all the time. This is one of the causes of many incurable diseases.

By supplying these minerals, we can activate the enzymes as well as the mitochondria in our bodies. People can directly experience its effect because when they drink this water, their body immediately heats up from the inside.

Not only that, but immune functions are improved as well. Therefore some cases have been seen where early-stage cancer was completely cured only by drinking these mineral waters. It was also reported that it treats blood glucose levels, blood pressure, and atopic dermatitis.

As we have discussed in previous chapters, the activation of mitochondria leads to the production of Cytochrome C that induces cancer cell apoptosis.

Another theory states that these minerals activate dormant genes to utilize proteins that attack the cancer cells.

Since the water is made from stones that are 70 million years old, it contains almost all of the minerals that exist on the earth. Some of these minerals may affect our bodies to function in special ways.

When the body is supplied with a sufficient amount of minerals, enzymes as well as mitochondria will be activated to supply energy in sick people.

Easy passage through the blood/brain barrier.
Activates mitochondria right away

Hydrogen capsules using potassium oxide produce hydrogen ion to effectively activate mitochondria. Potassium oxide was first introduced by a professor at one of the national universities.

Potassium oxide is combusted in the hydrogen gas to have a strong reduction power. Oxidation refers to objects binding with oxygen and reduction refers to objects taken away with enzymes. A good example is that rusting is oxidization and reduction is the removal of rust. Even though there were reduction waters being sold on the market, their hydrogen levels become very low when stored in cups and PET bottles for a long period of time.

However, our potassium oxide was reported to emit hydrogen for 5 days. It also had above 800Mv of reduction power. Hydrogen is a small atom that has 0.7 nanometers of diameter. It is able to invade any part within the cells.

In the hydrogen study by Professor Fukoda, rats with ischemic brains were prevented from brain damage when they inhaled 2% hydrogen gas. His study was published in the renowned science journal Nature.

Hydrogen penetrates deep into the cells and combines with oxygen radicals that show an 80% correlation with cancer, diabetes, myocardial infarction, brain infarction, allergy, glaucoma and other diseases. When hydrogen combines with oxygen radicals, it disintegrates the oxygen radicals into water and oxygen. That is how hydrogen can be therapeutic to the human body.

It shows immediate effects when inhaled into the body.

It disintegrates oxygen radicals within 30 minutes of administration. Since it activates mitochondria as well, it promotes energy production within weak patients. Even though the brain is equipped with a blood/brain barrier, hydrogen is able to pass this barrier without any resistance in order to affect our autonomic nervous system and hormone secretions.

Fucoidan's apoptosis induction method

Fucoidan is a well-known supplement that has a strong therapeutic effect on cancer. At the 55th Japanese Cancer Association's meeting held in 1996, "Research on fucoidan's anti-cancer effects" was published to tell the nation that fucoidan leads cancer cells into apoptosis while not damaging normal cells.

If the effects of fucoidan are the same for all cancers, we may no longer have to fear any type of cancer at all. The reason that we say that cancer is incurable is because cancer cells do not stop the replication process. Normal cells are programmed to die away when they reach a certain age. Cells also die when defects are detected within the cells.

This process is called apoptosis. However, cancer cells do not go into the apoptosis process even when they are damaged. In addition, while normal cells die after they have replicated for a certain amount of cycles, cancer cells do not have the function that counts its replication cycles. Cancer cells do not take orders from external signals. That is why cancer cells do not stop the replication process.

If we were able to completely remove cancer cells by surgery, cancer may not be so dangerous after all. However, since the cancer cells exist in every part of our body, it is important to induce apoptosis in cancer cells to prevent cancers from occurring in the first place.

If cancer cells did not replicate, a simple immune therapy may be sufficient enough to kill cancer cells. If the replication process is inhibited, attacks on cancer cells will become extremely effective.

Our body makes 3,000 to 6,000 cancer cells a day.

However, not everyone gets a cancer mass because their immune system fights off cancer cells every day. However, when the immune system is compromised, cancer cells will grow into a tumor mass. However, if we are able to induce the cancer cells' apoptosis by taking fucoidan, we can stop the cancer cell replication processes within the body.

High function supplements weaken cancer cells

A high concentration of vitamin C is toxic to cancer cells.

Much evidence is starting to back up nutritional treatment effects. One of the nutrition treatments that we use is the "high concentration vitamin C treatment". One of the scientists working in the NIH reported that a hi gh concentration of ascorbic acid (vitamin C) had a selective toxicity against cancer cells. Vitamin C's strong antioxidant effect produces an extremely large amount of hydrogen peroxide. Even though normal cells are able to neutralize hydrogen peroxide, cancer cells will die off because they cannot neutralize toxic hydrogen peroxide.

Therefore, vitamin C can have selective toxic effect on

cancer cells.

In other words, high concentrations of vitamin C have an effect like anti-cancer drugs. Since it does not have any side effects like other drugs, it may be applied to a wide range of patients. In fact, high concentrations of vitamin C are being used as anti-cancer drugs in some US institutions. We inject 50-70 grams of vitamin C into the patient's body each day.

Platinum and palladium materials promote oxidation and reduction to active organs in our body.

Since oxygen radicals are correlated with 90% of modern diseases, modern medicine is concentrating on how to deal with oxygen radicals. Professor Noguchi Hideo uses "Papral", a drug made from platinum and palladium, to handle oxygen radicals.

A colloid is a liquid where objects have been dispersed within. It has a good absorption rate within the body and produces hydrogen and oxygen to provide a strong oxidation and reduction power. Based on those effects, it is known to improve the immune function and increase the white blood cell count.

Since colloids are quickly absorbed into the cells, the hydrogen and oxygen made from platinum and palladium are directly provided to the cells' mitochondria. Then, the cells' oxidation and reduction functions will be strengthened as well as the toxic substance excretion function. Even though new drugs may have some side effects, Papral has minimal side effects. It was also reported that Papral has a 100-times greater effect in removing oxygen radicals than vitamin C. That is why we need to use this product to treat our patients.

Organic germanium produces interferons

Macrophages and NK cells are weakened as cancer progresses. That is why we treat our patients with organic germanium to compensate such mechanisms.

Organic germanium increases the enzyme level and activates the immune functions to massively produce interferons in our body. Therefore, interferons will reinforce the function of the macrophages and NK cells to attack the cancer cells in our body. Since organic germanium also acts as a semiconductor, it is able to deactivate the cancer cells' replication and even kill bacteria to prevent infections.

In addition, substances like placenta shots (harvested from human placentas) and garlic substances (multi-vitamins) may be used on patients depending on their condition.

The Garden Clinic Nakamachi's thermotherapy
and immune reinforcement therapy

6:00 Wake up. Breathe under the sunlight (breathing treatment) A walk after the reduced ion therapy (20 minutes), perform the reduced ion therapy again.

9:00 Breakfast Juice made from carrot, apple, cabbage and aloe. Miso soup (since mixers break down enzymes, it is cooked with low-pressure cooking methods)

10:00 (Rest)

  1. Reduced ion therapy (20 minutes)
  2. Integrated visible ray therapy (6 devices per person, 15-40 minutes)
  3. Hot gemstone therapy (60 minutes per therapy)
    — Drink 500c of mineral water before and after the treatment
  4. Hormesis host stone therapy (2 times in 5 minutes)
  5. Reduced ion therapy (for 30 minutes)

2:00 Lunch Udon, noodle, brown rice, radish, salad and other boiled vegetables

  • Ion reduction therapy (20 minutes)
  • Vitamin C, germanium, Paraple, Vitamin B17 and placenta shots
  • Integrated visible ray therapy (15~40 minutes)
  • Hot gemstone therapy
  • Hormesis hot stone therapy
  • Reduced ion therapy (20 minutes)

7:00 Dinner Grain food, sea food, traditional meal using linseed oil

  • Reduced ion therapy (15~40 minutes)
  • Carbonated water therapy (30 minutes)
  • Boil cupping therapy (60 minutes)
  • Traditional Thailand lymph massage

Free time (entertainment, movies, chatting, etc)

⊕ Supplements like fucoidan, black yeast, hydrogen capsules, enzyme drinks, and fermented beans may be taken during each meal based on the patient's status.

physical therapy methods

There are many physical therapy methods the cure various incurable diseses.

The garden improves the therapeutic effects of our treatments.